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The Magic Of Carboxymethyl Cellulose In Medicine
- Oct 27, 2016 -

CMC-injectable pharmaceutical industry as emulsifier and stabilizer, Tablet Binder and film-forming agents. Foundation and animal experiments show that anticancer drug carrier of carboxymethyl cellulose is safe and reliable. Carboxymethyl cellulose film used material, transformation of the development of traditional Chinese medicine of nourishing yin and promoting granulation dosage form---and nourishing yin and promoting granulation membrane, can be used for grinding surgical wounds and traumatic wounds of the skin. Animal model studies have shown that the membrane to prevent wound infection, no significant difference with the gauze dressing in controlling seeping wound fluid on the wound heal faster, this film is superior to gauze dressings, and reduce postoperative edema and stimulating the wound surface. PVA and carboxymethylcellulose sodium and CP 3:6:1 produced films for the best prescription, adhesion and release rates are increased, increasing sustained-release mucoadhesive film adhesion, extension agents in the mouth of the residence time of preparation and pharmacodynamics of drugs have improved significantly.

Ding Paika potent local anesthetic, but sometimes it can produce poisoning more serious cardiovascular side effects, while in broad clinical application of bupivacaine, control has been more emphasis on its toxicity. Pharmaceutical research showed, carboxymethyl cellulose as a slow-release material mixed with bupivacaine solution can significantly reduce the side effects of drugs. In PRK surgery, using low concentrations of tetracaine and non-steroidal anti-inflammatory drugs combined with CMC can significantly relieve postoperative pain. Prevention of postoperative peritoneal adhesions, reduce the incidence of obstruction is one of the issues of most concern in clinical surgery. Studies have shown that, reducing the level of postoperative peritoneal adhesion of carboxymethyl cellulose is superior to sodium hyaluronate, can be used as an effective way to prevent the occurrence of peritoneal adhesion. Carboxymethyl cellulose transcatheter hepatic arterial infusion of anticancer drugs for the treatment of hepatocellular carcinoma (THAI), can significantly prolong the residence time of anticancer drugs in cancer, improves anticancer abilities, enhance the treatment effect.